Uma Jolie was born in Fairbanks, California and she is of Mexican, Romanian, Hungarian, and German descent. She was raised in Woodland Hills, Los Angeles. She worked as a sales associate at Abercrombie & Fitch and as a bartender and stripper at a Los Angeles strip club before getting into porn.
Jolie entered the porn industry in the summer of 2014 and she did her first scene with Goldie Rush for Kissing Cousins. Although she did briefly perform in boy/girl scenes early in her career, she now performs only in girl/girl scenes. Her stage name is derived from the names of actresses Uma Thurman and Angelina Jolie. She currently resides in Miami, Florida.